Because the joints are capable of excessive motion in people with joint hypermobility syndrome, they are susceptible to injury. Symptoms of joint hypermobility syndrome include pain in the knees, fingers, hips, and elbows. There is a higher incidence of joint dislocation and sprains of involved joints. Scoliosis (curvature of the spine) occurs more frequently in people with hypermobile joints and can lead to back pain. Joint hypermobility tends to decrease with aging as we become naturally less flexible.

Signs of the syndrome include: